RELATIONSHIP OF CARDIOVASCULAR RISK MARKERS IN CHILDREN SGAAND AGA

Abstract

INTRODUCTION: Children born preterm usually experience an initial growth restriction, suggested to be caused by the immature organs and an inadequate nutritional intake.After this initial growth faltering, healthy preterm born children, and especially those born after 32 gestational weeks, usually fall back to the reference growth curve, following that of term born babies. For children born SGA, 80 % will experience a relative catch-up growth within the rst 6 months of life. OBJECTIVE: Role of different risk proles for children being born preterm vs being born SGA and early iron supplementation affect later cardiovascular risk RESULT: In Placebo group, 4.6(0.5) patients had Fasting glucose (mmol/L), 2.9(2.3-3.5) patients had Fasting insulin(µU/mL), 0.59(0.4-0.7) patients had HOMA-IR, 4.5(0.7) patients had Cholesterol(mmol/L), 0.58(0.2) patients had Triglyceride(mmol/L), 2.8(0.6) patients had LDL(mmol/L), 1.5(0.3) patients had HDL(mmol/L), 0.63(0.4) patients had ApoB(g/L and 0.20(0.1-0.6) patients had hs-CRP(mg/L). In Iron supplements group, 4.4(0.5) patients had Fasting glucose(mmol/L), 2.7(2.0-3.8) patients had Fasting insulin(µU/mL), 0.54(0.4-0.8) patients had HOMA-IR, 4.3(0.8) patients had Cholesterol(mmol/L), 0.59(0.3) patients had Triglyceride(mmol/L), 2.8(0.6) patients had LDL(mmol/L), 1.5(0.4) patients had HDL(mmol/L), 0.61(0.3) patients had ApoB(g/Land 0.24(0.2-0.8) patients had hs-CRP(mg/L). CONCLUSION: This literature showing that there is progression of these risk factors as children enter early adolescence. Further longer longitudinal studies are needed to elucidate the mechanisms responsible for progression of cardio-metabolic risk factors from infancy to adolescence in SGAand LGAsubjects.