Abstract

<p><strong>Objective: </strong>Prevalence of obesity and cardiovascular disease has increased in both urban and rural areas Indonesia. High body fat percentage (BF%) is associated with a high cardio metabolic risk. The apolipoproteins (Apo) B/Apo A-1 ratio is a better risk predictor for cardiovascular disease. This study aimed to explore the relationship of BF% and Apo B/Apo A-1 ratio among rural adults in Yogyakarta Indonesia. <strong></strong></p><p><strong>Methods: </strong>This cross-sectional study included 40 men and 62 women (40-60 y old). Those who had cardiometabolic diseases, edema or currently taking cardio metabolic medicines were excluded. Information about sociodemographic details was obtained by using a self-administerd questionnaire. The questionnaire also assessed smoking status, reproductive history and medical history. Anthropometric measurement, apo B, Apo A-1, fasting blood glucose and blood pressure were measured. <strong></strong></p><p><strong>Results: </strong>The prevalence of high BF% was 12.7% and 6.9% in men and women, respectively. There was negative correlation between BF% and apo A-1 and positive correlation between BF% and apo B as well as BF% and apo B/apo A-1 ratio. A significant weak correlation was observed between BF%-apo B/apo A-1 ratio in women (r: 0.280; p: 0.027).</p><p><strong>Conclusion</strong>:<strong> </strong>BF% is associated with apo B/apo A-1 ratio among women adults in rural area of Yogyakarta Indonesia findings support the importance of using BF% to predict cardiovascular disease in rural area.</p>

Highlights

  • The prevalence of obesity and cardiovascular disease (CVD) has increased in developing countries, including Indonesia [1,2,3]

  • A significant weak correlation was observed between BF%-apolipoprotein B (apo B)/apo A-1 ratio in women (r: 0.280; p: 0.027)

  • BF% is associated with apo B/apo A-1 ratio among women adults in rural area of Yogyakarta Indonesia findings support the importance of using BF% to predict cardiovascular disease in rural area

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Summary

Introduction

The prevalence of obesity and cardiovascular disease (CVD) has increased in developing countries, including Indonesia [1,2,3]. Based on the household health survey in Indonesia (2004), the study demonstrated that the prevalence of overweight was 7.2% and 10.4% for men and women, respectively. A national survey showed that the highest incidence of central obesity was 36.9% among adults 45 to 54 y old, and the percentage of abnormal low-density lipoprotein (LDL) and highdensity lipoprotein (HDL) profile is more prevalent in rural Indonesia. The CVD prevalence was greater in urban compared with rural population (23.4% and 19.5%, respectively) [2]. Another study indicated that the prevalence of prehypertension and hypertension were relative high among young Indonesian adults in primary health care of rural area [4]. The increased of obesity is closely associated with elevated risk of CVD and obesity is an independent risk factor for all-cause mortality as well as for CVD [7, 8]

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