Abstract

Background and aimsFacial flushing after drinking alcohol, common among Asians, is a phenotype for genes involved in alcohol metabolism. MethodsWe investigated cross-sectional associations between flushing, alcohol use, blood pressure (BP) and HbA1c among (n = 287) Cambodians with dysglycemia in Cambodia and in the U.S. Participants were categorized as Abstainers, Flushers who drink, or Non-flushers who drink. ResultsFlushers and Non-flushers had similar alcohol use. Flushers had higher BP than Non-flushers and Abstainers, even after controlling for confounders. Findings were similar across countries. Drinkers had higher HbA1c than Abstainers. ConclusionsFuture research should examine whether reducing alcohol improves cardiometabolic outcomes.

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