Relationship between vitamin D level and ovarian reserve markers in infertile women in Diyala province, Iraq

Abstract

Objective: To investigate the relationship between vitamin D and antral follicles (AFC) and anti-Mullerian hormone (AMH) . Methodology: This cross-sectional study was conducted on infertile women. Patients had to be married, between the ages of 18 and 40, without a history of chronic illnesses, abstain from drug use, not have any specific gynecological diseases, as determined by the gynecologist who oversaw the project, and have an AFC count of less than 10 in sonography between less than 10 in sonography during early follicular period. Additionally, their AMH levels were lower. Results: The study included 99 females with mean age of 29±6 years. Majority were over 21; 46.9% had college degrees, 53.1% were housewives, 83.7% were nonsmoking. Overweight women were 48.48% and obese were 3.13%. AFC and AMH significantly rose with vitamin D supplementation. Also, mean vitamin D levels fluctuated following supplementation. Conclusion: Vitamin D has a promising influence on AMH expression. Vitamin D boosts AMH levels with increase in the number of antral follicles or ovarian reserve.