Abstract

To investigate the association between vitamin D levels and hyperglycemia in a national community sample of older people. Cross-sectional, nationally representative sample. Community. Two thousand thirty-eight noninstitutitionalized adults aged 65 and older taking part in the Health Survey for England 2005. Serum 25-hydroxy vitamin D (25(OH) D) levels, glycosylated hemoglobin (HbA1c), and covariates: age, sex, social class, season of examination, use of vitamin supplements, and physical health status. Hyperglycemia was independently associated with low vitamin D levels (odds ratio (OR)=2.30, 95% confidence interval (CI)=1.20-4.42 for 25(OH)D<25.0nmol/L and OR=2.09, 95% CI=1.22-3.58 for 25(OH)D25.0-49.9nmol/L) but not for 25(OH)D between 50.0 and 74.9nmol/L (OR=1.49, 95% CI=0.85-2.62). The higher-than-expected co-occurrence of low vitamin D levels and hyperglycemia (HbA1c≥ 6.5%) are important public health concerns for older populations living in northern latitudes because both are common, and both have substantial adverse health consequences. Ensuring adequate vitamin D levels may help reverse the increasing trend in the development of diabetes mellitus and related complications in older people.

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