Relationship between uterine scoring system for reproduction and pregnancy in controlled ovarian stimulation-intrauterine insemination cycles

Abstract

Aims: (1) Evaluation of uterine scoring system for reproduction (USSR) score in controlled ovarian stimulation-intrauterine insemination (COS-IUI) cycles. (2) Evaluation of the relationship between USSR score and pregnancy in COS-IUI cycles. Settings and Design: Prospective observational study. Materials and Methods: The study comprised women visiting the department with unexplained infertility for a COS-IUI cycle. A total of 30 cycles were inducted. Baseline transvaginal sonography (TVS) was performed on day 2 of the cycle. Stimulation was performed with clomiphene citrate (50 or 100 mg). On day 5, the recruitment and dominance of follicles were studied by TVS. In the absence of dominance and/or in need of increase in recruitment, urinary gonadotropin was administered. TVS was repeated every 2 days until the dominant follicle was 15 mm and then on a daily basis till follicle reached 18 mm. USSR score was then evaluated and injection. Human chorionic gonadotropin (HCG) 10,000 units was given for follicular rupture. IUI was done 34–36 h posttrigger with prepared semen samples containing at least 15 million motile sperms. Women with serum β HCG values of ≥ 25 IU/ml on the 16th post-IUI day were pregnancy positive. Statistical Analysis: Chi-square test. Results: None had a USSR score of 20. Two had a score of 17–19, two had score of 14–16, 26 had a score of ≤13. Of the 30 women, three conceived. Two of the three had a score of 17 and one had a score of 16. Conclusions: USSR can prove to be a simple, noninvasive, and authentic score to predict the uterine environment and help in the prediction of outcome.