Relationship Between Triglyceride-Glucose Index and Microvascular Complications in Hospitalized Patients with Type 2 Diabetes Mellitus

Abstract

Aim: The increasing prevalence of diabetes mellitus (DM) brings about a rise in nephropathy, retinopathy, and neuropathy, which are microvascular complications of diabetes. The triglyceride-glucose (TyG) index is a convenient indicator of insulin resistance. It is related to microvascular and macrovascular complications among nonhospitalized patients with diabetes. However, it is unclear if the TyG index poses risks for vascular complications of type 2 DM in hospitalized patients. This study aims to investigate possible relations between this index and the risk of microvascular complications in hospitalized patients with type 2 DM. Material and Methods: The present study included 420 type 2 DM patients who were hospitalized in our clinic between February 2019 and May 2022. The TyG index was measured as fasting triglycerides mg/dL × fasting glucose mg/dL/2. The presence of microalbuminuria (MAU), diabetic neuropathy, chronic kidney disease (CKD), and retinopathy (DR) were evaluated. The data were analzed using IBM SPSS 22.0 statistical software. The level of statistical significance was taken as p