Abstract
Recently with the rapid development of the high-intensity focused ultrasound (HIFU) in biomedical ultrasound, much attention has been paid to the noninvasive temperature estimation in biological tissue in order to determine the region and degree of the ultrasound-induced lesions. In ultrasound hyperthermal therapy it is highly desirable to study the real-time noninvasive monitoring of temperature distribution in biological tissue. In this paper, the relationship between the nonlinearity parameterB/A and the temperature in biological tissue is studied and compared with the theoretical model as well as the experimental results from the thermocouple. Results indicated thatB/A could be used as an effective tool to monitor the temperature distribution in biological media.
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