Abstract
Pollution of the environment with chemical compounds (CC) as a result of active industrial activity of man has raised an acute problem of evaluating the biological hazard of CC for living system. The results of this work suggest that the carcinogenic activity of aromatic amines is determined by the ratio of the rates of two competing processes, binding of the aromatic portion of an amine molecule to DNA, and the elimination of CC from the organism. In this case, the processes of metabolic activation of aromatic amines occur equally easily for carcinogens and noncarcinogens.
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