Abstract
Objective To investigate the relationship between the changes of bone marrow megakaryocyte count and therapeutic effect in adults with immune thrombocytopenia. Methods From January 2009 to June 2013, 140 adult immune thrombocytopenia patients were selected as the research objects, all of the patients were performed with bone marrow megakaryocyte smears before treatment, the number of megakaryocyte 35/cm2 classified as group Ⅲ, three groups of patients were treated in the same solution, the treatment effects of three groups of patients were compared. Results The total effective rate of group I, Ⅱ and Ⅲ was 25.00%, 76.47% and 93.33%, the difference was significant between group I and Ⅱ(χ2= 9.961, P<0.01), group I and Ⅲ(χ2= 40.279, P<0.01), group Ⅱ and Ⅲ(χ2 =5.424, P<0.05). Conclusions The number of bone marrow megakaryocyte in adult patients with immune thrombocytopenia has great influence on the therapeutic effect, proliferation of bone marrow megakaryocyte is beneficial to treatment. Key words: Immune thrombocytopenia; Bone marrow megakaryocyte; Treatment effect; The number of changes
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