Relationship between the AB0 Blood System and Proximal Femoral Fracture Patterns in the Turkish Population.

Tolgahan Kuru,Haci Ali Olcar

doi:10.1155/2020/1834525

Abstract

Objective AB0 blood groups have shown to be associated with increased risk of several orthopedic disorders such as Achilles tendon rupture and hip osteoarthritis. The objective of this study was to investigate relationships between the AB0 blood system and hip fracture patterns, duration of hospitalization, and amount of blood transfusion. Methods Data of 308 patients treated due to hip fractures in our hospital between 2017 and 2019 were evaluated. Epicrisis reports and X-rays of the patients included in this study were retrospectively screened, and hip fractures were classified as intracapsular and extracapsular fractures. Patients were divided into A, B, 0, and AB groups according to blood groups. Results The mean age of the patients was 75.54 ± 13.5 years. Of all patients, 103 had an intracapsular fracture and 205 had an extracapsular fracture. No statistically significant correlation was found between blood groups and fracture patterns. No statistically significant difference was found between the amounts of transfusion according to the blood groups, and no significant difference between the durations of hospitalizations according to the blood groups. Conclusion In our study population, we could not find a significant relationship between the AB0 blood system and fracture patterns. We think that these potential relationships could be explained with further comprehensive studies with larger populations.

Highlights

Hip fractures remain the most important fracture because of poor survival and requiring immediate surgery
The association between the distribution of AB0 blood groups and osteoporosis has been confirmed [13]. These findings suggest that the gene and enzymes in the AB0 system have pleiotropic roles
Patients were divided into A, B, 0, and AB groups according to blood groups, in order to determine whether blood pressure was associated with fracture patterns, amount of transfusion, and duration of hospitalization

Summary

Introduction

Hip fractures remain the most important fracture because of poor survival and requiring immediate surgery. Proximal femoral fractures account for a significant part of hospitalizations among trauma cases. The overall number of proximal femoral fractures is constantly increasing worldwide [1]. Hip fractures are an important cause of morbidity and mortality, resulting in increasing healthcare costs. Intracapsular and extracapsular fractures have different bone composition, proximal femoral geometric parameters, epidemiology, and clinical characteristics [3, 4]. Parathyroid hormone, vitamin D, distribution of bone mass density, proximal femoral geometry, lifestyle, and nutritional status are the possible related causes [6, 7]. People with increased parathyroid hormone level in response to vitamin D insufficiency tend to have extracapsular fractures, while persons with muted parathyroid hormone response presented more commonly due to intracapsular fractures

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Discussion

Conclusion