Relationship between the 10-Year Risk for Atherosclerotic Cardiovascular Disease and the Dietary Inflammatory Index among Korean Adults Based on the Seventh Korea National Health and Nutrition Examination Survey (KNHANES).

Abstract

Worldwide, atherosclerotic cardiovascular diseases (ASCVD) are the leading cause of death and are considered a major public health concern. Exposure to repeated inflammation may contribute to the development of ASCVD, and diet plays a vital role in inflammation. In this study, we explored the correlation between the dietary inflammatory index (DII) and the 10-year ASCVD risk in Korean adults. We used multistage, stratified sampling to analyze a representative sample of Korean adults aged 40-64 years from the 7th Korea National Health and Nutrition Examination Survey data. Logistic regression was carried out to evaluate the association between 10-year high risk for ASCVD and dietary variables including DII. Participants were separated by quartiles, from Q1 to Q4, according to DII scores. Participants in the Q1 group had the lowest DII scores indicating a more anti-inflammatory diet. Participants in the Q4 group had the highest DII scores indicating more proinflammatory diets. Estimated risk of ASCVD results was categorized into the low-risk (less than 7.5% risk) and high-risk (greater than 7.5% risk) groups. In men, participants in the Q3 group had a risk for ASCVD of 1.20 times higher than the Q1 group participants and participants in the Q4 group had a risk of 1.34 times higher than the participants in the Q1 group. In women, ASCVD risk was not significantly associated with DII scores. These results provide systematically analyzed evidence for dietary interventions in ASCVD prevention efforts, especially in men.