Abstract
RATIONALE: Bronchial asthma is physiologically characterized by variable airflow obstruction and airway hyperresponsiveness (AHR). Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis and enhancer of vascular permeability with subsequent edema and thereby contributes to the pathogenesis of asthma. The aim of the present study was to investigate a relationship between serum VEGF levels and methacholine AHR in asthmatic children.
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