Relationship between serum magnesium level with vascular calcification and mineral disorder in patients on continuous ambulatory peritoneal dialysis

Abstract

Objective To explore the relationship between serum magnesium level, abdominal aortic calcification(AAC) and mineral metabolism in continuous ambulatory peritoneal dialysispatients. Methods Sixty-two cases patients who were on Continuous Ambulatory Peritoneal Dialysis in Pritoneal Dialysis Center of Qingdao Municipal Hospital were enrolled prospectively.The AAC was detected by abdomen lateral plain radiographs, and the AAC score(AACs) was calculated.According to the AACs, the patients were divided into group A(AACs≤4 points) and group B(from >4 point to ≤15 point) and group C(AACs>15 point). And collected the patient′s clinical data and blood biochemical indicators.The serum magnesium levels of 3 groups were observed, and explored the relationship of serum magnesium and intact parathyroid hormone(iPTH), serum calcium, serum phosphorus. Results There were 41 cases of vascular calcification in 62 cases maintenance ambulatory peritoneal dialysis patients, and its incidence was 66.13%.Group levels of serum magnesium were in group A was (1.00±0.18) mmol/L, (0.89±0.10) mmol/L of group B, and (0.75±0.13) mmol/L of group C, the mean differences were significant(F=11.99, P 0.05). Conclusion Vascular is the calcification frequent complications in continuous ambulatory peritoneal dialysis patients.The serum level of serum magnesium may be correlated with the AAC, iPTH, serum phosphorus. Key words: Peritoneal dialysis; Serum magnesium; Vcular calcification; Calinosis