Abstract

The effects of the food intake pattern on the activity and fraction pattern of serum γ-glutamyl transpeptidase (γ-GTP) were examined in 257 healthy Japanese men.Applying the technique of factor analysis to the food intake data, the following three factors were extracted. The first factor (F1): meats, eggs, and vegetables had a highly positive factor loading. The second factor (F2): wheat had a highly positive factor loading, while rice had a highly negative factor loading. This factor was considered to be a “wheat versus rice factor”. The third factor (F3) could not be explained simply in terms of its factor. The scores of the first two factors for the 257 subjects were calculated.Significantly negative correlations were observed between the percentage of GT1 fraction and the factor score of F1 (r=-0.230, p<0.01), between the percentage of GT1 fraction and the factor score of F2 (r=-0.187, p<0.01). The total serum γ-GTP activity was not correlated with the factor score. These results suggested that the percentage of GT1 fraction is influenced by the pattern of food intake.

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