Relationship between Pwave peak time and coronary artery disease severity in non-ST elevation acute coronary syndrome.

Abstract

Early diagnosis of non-ST elevation acute coronary syndrome (NSTE-ACS) and prediction of the severity of current coronary artery disease (CAD) play amajor role in patient prognosis. Electrocardiography has aunique value in the diagnosis and provides prognostic information on patients with NSTE-ACS. In the present study, we aimed to examine the relationship between Pwave peak time (PWPT) and the severity of CAD in patients with NSTE-ACS. Atotal of 132 consecutive patients (female: 35.6%; mean age: 60.1 ± 11.6years) who were diagnosed with NSTE-ACS were evaluated retrospectively. Gensini scores (GSs) were used to define the angiographic characteristics of the coronary atherosclerotic lesions. The patients were divided into two groups according to the GS. The PWPT was defined as the duration between the beginning and the peak of the Pwave, and Rwave peak time (RWPT) was defined as the duration between the beginning of the QRS complex and the peak of the Rwave. There were 59 (44.6%) patients in the high-GS group (GS ≥25) and 73 (55.3%) patients in the low-GS group (GS <25). Presence of diabetes mellitus, low left ventricular ejection fraction, and high RWPT and PWPT were identified as predictors of ahigh GS in the study population. There was no significant difference between the area under the curves of PWPT and RWPT for predicting the severity of CAD (0.663 vs. 0.623, respectively; p = 0.573). The present study found that both PWPT and RWPT on admission electrocardiography were associated with the severity and complexity of CAD in patients with NSTE-ACS.