Relationship between premature ventricular contractions and serum TNF-α, IL-6 level in patients

Abstract

Objective: To investigate the relationship between premature ventricular contractions and serum TNF-α, IL-6 level. Methods: From December 2020 to April 2021, 35 patients with premature ventricular contractions of coronary heart disease with deficiency of both qi and Yin in our hospital were selected as the observation group, and 41 healthy people in the same period were selected as the control group. Serum samples were collected from the observation group and the control group, The expression levels of TNF-α, IL-6 in serum were detected by ELISA; Objective to evaluate the relationship between lown classification of ventricular premature beat and TCM symptom score of patients with coronary heart disease of Qi and yin deficiency type; The relationship were measured between serum TNF-α, IL-6 level and lown grade of ventricular premature beat in the observation group. Results: Compared with the control group, the levels of serum TNF-α, IL-6 in the observation group were significantly higher; With the improvement of lown classification of ventricular premature beat, TCM symptom score and the levels of serum TNF-α, IL-6 are increased step by step. Conclusion: The relationship between premature ventricular contractions and serum TNF-α, IL-6 in patients with coronary heart disease of Qi Yin deficiency type may provide some theoretical value for clinical treatment.