Abstract
The membrane proteins require lipids in order to express their function. The function is under the influence of structure and physical properties of the lipid membrane surrounding the proteins. The non-bilayer structure induced by non-bilayer forming lipids is concerned in various membrane functions, such as membrane fusion during endocytosis. The physical properties of non-bilayer forming lipids are investigated by fluorescence measurements using an environment-sensitive probe, laurdan, differential scanning calorimetry and density meter. The results suggest relationship between the physical properties of non-bilayer forming lipid and the membrane functions.
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