Relationship between physical activity and cognition function among people aged 55 and above in 4 provinces of China

Abstract

Objective To analyze the relationship between different intensity of physical activity(PA) duration and cognitive function. Methods The 2018 Community-based Cohort Study on Nervous System Diseases used multi-stage stratified cluster randomization sampling method to select study participants. A total of 5571 participants aged 55 years and above from four provinces in China with complete information on demographic characteristics and PA and cognitive function were included in the final analysis. Basic information and PA data were collected by questionnaire. The Montreal cognitive assessment(MoCA) score method was adopted to evaluate the cognitive function. Light physical activity(LPA) duration and moderate-to-vigorous physical activity(MVPA) duration were calculated. Multivariate Logistic regression and Multiple linear regressions were used to analyze the relationship between different intensity of PA duration and the risk of mild cognitive impairment(MCI) and MoCA total score. Results The median(P25, P75) of LPA and MVPA were 7. 0(0. 0, 16. 3) and 7. 3(0. 0, 14. 0) hours per week in the non-MCI group among 5571 participants aged 55 years and above in four provinces of China in 2018. In the MCI group, the median duration were 9. 3(0. 0, 17. 5) and 7. 0(0. 0, 11. 7) hours per week. The Logistic analysis showed that the OR of MCI was 0. 63(95%CI 0. 49-0. 82, Pl0. 05) for the elderly with 3. 6-7. 0 hours of MVPA per week, compared to the elderly without MVPA. The OR of MCI was 1. 26(95%CI 0. 94-1. 67, Pg0. 05) for the elderly with 3. 6-7. 0 hours of LPA per week compared to the elderly without LPA. Multiple linear regression analysis showed that compared to the elderly without MVPA, the total MoCA score increased with LPA duration increased as the duration was less than 10. 5 hours per week. The MoCA score decreased with LPA duration increased as duration was between 10. 5 and 21. 0 hours per week. Conclusion MVPA duration increment was associated with decreased prevalence of MCI and increased cognitive function in the elderly in four provinces of China. LPA duration should be maintained at an appropriate level in order to reduce the incidence of MCI and increased cognitive function in the elderly.