Abstract
ObjectiveTo observe the associations between regional peripheral refraction and myopia development in young Chinese people.MethodsTwo hundred and forty-one young adult subjects (21 emmetropes, 88 low myopes, 94 moderate myopes, and 38 high myopes) aged 18–28 years were included, and only the right eyes were tested. Eye biometrics were measured before pupil dilation using the Lenstar. Relative peripheral refractive errors (RPRE) were measured after pupil dilation using multispectral refractive topography (MRT), at nine retinal eccentricities: 0–5, 5–10, 10–15, 15–20, 20–25, 25–30, 30–35, 35–40, and 40–45 degrees.ResultsIn this study, RPRE increased with eccentricity, and it shows a growing trend with the increase of the degree of myopia among emmetropia, low myopia and moderate myopia groups, and RPRE varied with myopia severity at eccentricities between 20 and 35 degrees only. In addition, axial length (AL) and RPRE were positively correlated between 20 and 45 degrees, and AL was an independent risk factor for RPRE between 20 and 35 degrees.ConclusionThese findings indicate that the eccentricities between 20 and 35 degrees RPRE may be closely related to refractive development and eye growth in young Chinese people.
Highlights
Peripheral hyperopic defocus has been an area of research interest in the pathogenesis of myopia in recent years and peripheral refraction is of great significance in the field of vision research.Studies have shown that the human visual system can recognize signs of defocus and change its axial length, causing the retina to migrate toward the defocused image plane [1,2,3,4,5]
Subjects were classified into four refractive groups according to central spherical equivalent (SE) refractive error: Emmetropia group (E, +0.5 to −0.5 D), Low Myopia group (LM, −0.50 to −3 D), Moderate Myopia group (MM, −3 to −6 D), and High Myopia group (HM, >-6 D) (Figure 1)
At all eccentricities apart from those between 30 and 45◦, the relative peripheral refractive errors (RPRE) increased with myopia severity
Summary
Two hundred and forty-one young adult subjects (21 emmetropes, 88 low myopes, 94 moderate myopes, and 38 high myopes) aged 18–28 years were included, and only the right eyes were tested. Eye biometrics were measured before pupil dilation using the Lenstar. Relative peripheral refractive errors (RPRE) were measured after pupil dilation using multispectral refractive topography (MRT), at nine retinal eccentricities: 0–5, 5–10, 10–15, 15–20, 20–25, 25–30, 30–35, 35–40, and 40–45 degrees
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