Relationship Between Peak Oxygen Pulse and Heart Rate Recovery in COPD Patients During an Incremental Cardiopulmonary Exercise Test in Cycle Ergometer

Abstract

SESSION TITLE: Pulmonary Physiology SESSION TYPE: Original Investigation Poster PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM PURPOSE: It has been previously described that patients with chronic obstructive pulmonary disease (COPD) have showed a decreased peak oxygen pulse (O2 pulse), but the relationship with the levels of heart rate recovery (HHR) percentage has not been described clearly. METHODS: It is a non-experimental descriptive study transactional. The total sample (N = 100) included a group of patients with COPD (n = 33) and a group of healthy subjects (n = 67), including men and women between 46 and 69 years for the first group included and between 16 and 57 years for the second. All patients performed spirometry, and symptom-limited cardiopulmonary exercise test (CPET). We analyzed maximal work (Watts), oxygen consumption, O2 pulse, exercise time, maximal heart rate and post exercise heart rate recovery on the third minute in cycle ergometer. RESULTS: We found a significant reduced peak oxygen pulse and the percentage of the heart rate recovery in patients with COPD compared to healthy subjects ( 9.7 ± 0.6 was found and 25.7 ± 2.1 % vs . 14.2 ± 0.6 and 91.8 ± 3.2 % ; p < 0.001 respectively). COPD patients showed that those patients with low maximum pulse or showed a lower percentage of heart rate recovery in the third minute, but the correlation was not statistically significant ( Spearman r: 0.19 ; range -0.17 to 0.5 Between; p = 0.28 ) . The control group showed greater variability correlated with greater or lesser association (Spearman r: 0.6 , range -0.19 to -0.31 p = 0.6). CONCLUSIONS: The present study showed that COPD patients in addition to marked reduction of work capacity and lower exercise duration are associated with lower O2 pulse and delay in exercise heart rate recovery more than healthy subjects. CLINICAL IMPLICATIONS: These data suggest that Pulse O2 and HHR should be evaluated in patient with COPD in clinical practice and pay more attention to HHR in the intervals inter and intra exercise recovery during rehabilitation programs. DISCLOSURE: The following authors have nothing to disclose: Xavier Bocca, Claudio Xavier, Glenda Ernst, Alejandro Salvado No Product/Research Disclosure Information