Abstract

Objectives: Patients undergoing 18F-FDG PET/CT imaging are considered external radiation sources. Accurate dose rate estimates are important for conducting realistic risk assessments and performing dose reconstruction in cases of accidental exposures. The patient radiation self-attenuation factor is assumed to be a function of the patient’s body size metrics, but we can use these metrics to predict the dose rate around the patients with accuracy. The objective of this work was first to measure the patient attenuation factor by performing direct dose rate measurements from patients undergoing PET/CT imaging studies using 18F-FDG. The second objective was to study the possible correlation between the measured dose rate constant per unit activity from the patients and their body size metrics; five metrics were tested in this work. The last objective was to measure the patients’ voiding factor. Methods: We have measured dose rates at one meter from 57 patients and noted the patient’s height (H), weight (W) and calculated patient size metrics namely: Equivalent Cylindrical Diameter (ECD), Equivalent Spherical Diameter (ESD) and the Body Mass Index (BMI). Results: The measured average dose rate was 92.2 ± 14 μSv·h-1·GBq-1 measured at one meter. Therefore, the dose rate constant of 92 μSv·h-1·GBq-1 proposed by the AAPM, TG-108 report is adequate for radiation protection purposes. There was no statistically significant correlation between the dose rate constant per unit activity and the patient body size metrics. We have measured a patient voiding factor of 0.89 ± 0.06 in comparison with 0.85 recommended by the AAPM. Conclusions: The presented data can be used by medical physicist working in nuclear medicine in formulating more accurate risk estimations resulting from radiation exposure from patients undergoing 18F-FDG PET/CT imaging.

Highlights

  • The estimated dose rate at certain distance from a radioactive source depends on the dose rate constant, the source activity and the distance between the source and the measurement point

  • The dose rate constant of 92 μSv∙h−1∙GBq−1 proposed by the association of physicist in medicine (AAPM), TG-108 report is adequate for radiation protection purposes

  • The presented data can be used by medical physicist working in nuclear medicine in formulating more accurate risk estimations resulting from radiation exposure from patients undergoing 18F-fluorodeoxyglucose 18F (FDG) positron emitted tomography/computed tomography (PET/CT) imaging

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Summary

Introduction

The estimated dose rate at certain distance from a radioactive source depends on the dose rate constant, the source activity and the distance between the source and the measurement point. Once the radioactivity is incorporated into the patient, it will depend on his body tissues attenuation properties. Accurate dose rate estimates are important for radiation protection specialists conducting risk assessments and performing dose reconstruction in cases of accidental exposures. The American association of physicist in medicine (AAPM) in their report TG-108 shielding design for positron emitted tomography/computed tomography (PET/CT) imaging facilities recommends the use of a dose rate constant of 92 μSv/h/GBq for Fluorine-18 based compounds in situation where the patient is considered the source of radiation exposure [1]. In the same AAPM report, it is suggested to use a patient voiding factor of 0.85 in order to take into account the decrease in the total injected radioactivity due to voiding before imaging the patients in general

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