Year-end Sale % OFF 
Abstract
At present, there is growing interest in research examining the relationship between occupational stress and mental health. Owing to the socioeconomic impact of occupational stress and the unique environment of petroleum workers in Xinjiang, a cross-sectional study was carried out between April and December 2015 to investigate the relationship between occupational stress, 5-hydroxytryptamine receptor (5-HTR2A) genotype, and mental health. A total of 1485 workers were selected. The Symptom Checklist 90 was used to assess nine classes of psychological symptoms. Work-related stressors were evaluated using the Occupational Stress Inventory-Revised Edition. Levels of 5-HTR2A (the Tl02C and A-1438G single nucleotide polymorphism in the 5-HTR2A gene) were measured by polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP). The findings of the present study revealed a high prevalence rate of mental health problems (40.29%) in petroleum workers stationed in the arid desert, and suggested a strong correlation between occupational stress and mental health. The TC and CC genotype of Tl02C were found to be protective factors against mental health problems (odds ratio (OR) = 0.455, 95% confidence interval (CI): = 0.269–0.771, odds ratio (OR) = 0.340, 95% confidence interval (CI): 0.162–0.716). AG and GG genotype of A-1438G [odds ratio (OR) 1 = 2.729, 95% confidence interval (CI): 1.433–5.195; odds ratio (OR) 2 = 2.480, 95% confidence interval (CI): 1.221–5.037] were revealed as risk factors. These data provide evidence that occupational stress and 5-HTR2A gene polymorphism contributes to the incidence of mental health problems.
Highlights
Due to the rapid development of society, science, technology, and the organization of the labour process as well as changes to ways of life, occupational stress has been shown to be an important social determinant of health that negatively impacts workers [1,2]
While a statistically significant difference was found between the mental health problems group and normal group with regard to alcohol consumption (p = 0.009), there were no statistically significant differences for all other variables
T102C gene polymorphism, the results revealed that carrying the TC and CC genotypes acts as a protective factor against mental health problems (OR = 0.455, 95% confidence interval (CI) = 0.269–0.771; odds ratio (OR) = 0.340, 95% CI = 0.162–0.716)
Summary
Due to the rapid development of society, science, technology, and the organization of the labour process as well as changes to ways of life, occupational stress has been shown to be an important social determinant of health that negatively impacts workers [1,2]. Psychological health is “a state of wellbeing in which the individual realizes his or her own abilities, can cope with the normal stresses of life, can work productively and fruitfully, and is able to make a contribution to his or her community” [3]. There is increased interest in research examining the relationship between occupational stress and mental health [4,5,6,7,8]. Res. Public Health 2017, 14, 402; doi:10.3390/ijerph14040402 www.mdpi.com/journal/ijerph
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Environmental Research and Public Health
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
