Relationship between Liver Enzymes and Underlying Diseases in COVID-19 Patients admitted to Bam Pasteur Hospital in the First Six Months of 2021

Abstract

Introduction: The COVID-19 disease has emerged from December 2019 in Wuhan, China. The disease can affect many organs of the body, mainly organs associated with respiratory distress syndrome, but liver damage has also been reported. The present study aimed to investigate the relationship between liver enzymes and underlying diseases in COVID-19 patients admitted to Pasteur Hospital in Bam, Iran, in the first six months of 2021. Method: In this cross-sectional descriptive-analytical research, the study population consisted of COVID-19 patients admitted to Bam Pasteur Hospital. A researcher-made checklist was used to collect data regarding liver enzyme levels in people with underlying diseases. After data collection, the data were entered into SPSS software (version 22) and analyzed. Results: According to the findings of this study, a significant relationship was found between diabetes and variables such as age, ALP, and direct bilirubin. In addition, a significant relationship was observed between blood pressure and variables such as age, ALP(Alkaline Phosphatase), SGOT(serum glutamic-oxaloacetic transaminase), SGPT (serum glutamic-pyruvic transaminase), and direct bilirubin. Although heart disease was also significantly associated with variables such as age and SGOT, the results showed no significant relationship between addiction and variables such as age, SGOT, SGPT, ALP, total bilirubin, and direct bilirubin. Conclusion: Liver enzymes could be a warning sign of liver disease. It is recommended to screen COVID-19 patients for liver enzymes during the disease and be examined and treated