Relationship between isoflavone intake and metabolic syndrome diagnostic components in Korean postmenopausal women

Abstract

Recent studies have suggested that natural agents such as isoflavones, resveratrol, and anthocyanin have beneficial effects on metabolic syndrome (MetS)‐related disorders. The objective of this study was to evaluate among isoflavone intake, urinary isoflavone level, and the risk of MetS among Korean postmenopausal women. The subjects included 46 MetS and control (n=60). The MetS risk score was determined by adding the number of risk factors such as waist circumference and high levels of triglyceride (TG), HDL‐cholesterol, glucose, and blood pressure (BP). Dietary isoflavone intake was not significantly different between MetS and control groups; however, the urinary daidzein level was significantly higher in MetS subjects compared to that of the controls. Subjects with high TG had higher urinary daidzein and isoflavone levels than those without such abnormalities. The correlation analysis indicated that dietary isoflavone intake had a positive relation with energy intake. After adjusted energy intake, there was no significant relationship among isoflavone intake, metabolic syndrome, and its components in Korean postmenopausal women. These results indicate that women who have more dietary isoflavones tend to have more energy. Furthermore, this study shows no significant direct relationship between isoflavone intake and risk of MetS in Korean postmenopausal women.