Relationship between intracellular magnesium level, pulmonary function and asthma control level in patients with bronchial asthma

Abstract

Objective To investigate the relationship between intracellular magnesium level, pulmonary function and asthma control level in patients with bronchial asthma (asthma). Methods Selected 242 patients with asthma in Exhibition Road Hospital of Xicheng District of Beijing from January 2017 to June 2018, 242 patients with asthma were divided into complete control group (n=52), well-controlled group (n=109) and uncontrolled group (n=81). Lung function, serum and erythrocyte magnesium ion levels were observed. Results Forced expiratory volume in one second as a percentage of expected value (FEV1%pred) and maximal mid-expiratory flow as a percentage of expected value (MMEF%pred) in complete control group were higher than those in well-controlled group and non-controlled group, the difference was statistically significant (F=83.054, 67.821, both P 0.05), and there was no significant difference in plasma magnesium ion level between the three groups (F=0.638, P>0.05). The level of erythrocyte magnesium ion in the fully controlled group was higher than that in the well-controlled group and the non-controlled group, and the level of erythrocyte magnesium ion in the well-controlled group was higher than that in the uncontrolled group (F=137.083, P 0.05). Erythrocyte magnesium ion level was positively correlated with ACT (r=0.576, P 0.05). Conclusions There is no correlation between serum magnesium ion level and asthma control level, but there is a positive correlation between erythrocyte magnesium ion level and asthma control level. Key words: Asthma, bronchial; Pulmonary function; Asthma control level; Magnesium ion