Abstract
Sepsis remains the leading cause of death of patients in pediatric intensive care unit.The adaptive immune dysfunction affects the occurrence and development of sepsis.Recent studies have found that interleukin-7 plays a critical part in the immune cell activation, proliferation and maturation, and it may have important means in the immune reconstitution in sepsis.Immunosuppression, the biological function of interleukin-7, the immune cell regulation and its application progress in sepsis were reviewed in this article. Key words: Sepsis; Interleukin-7; Immune regulation; Children
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