Relationship between IL-20 and diabetic nephropathy in AL Anbar governorate

Abstract

Background: Diabetic syndrome is characterized by increase blood sugar and resistance to insulin. It is linked to macrovascular and microvascular complication such as nephropathy, neuropathy, and retinopathy. The aim of this study to investigate the relationship between Interleukin 20 and diabetic nephropathy. Material and Methods: The study was include 36 of them with type 2 diabetes, 23 of them with diabetic nephropathy, and 25 healthy controls population , all of whom were over the age of 40. ELISA was used to calculate the Interleukin 20 concentration. fasting serum sugar, Glycated Hemoglobin, Urea, Creatinine, Total protein, Albumin, and globulin were all found. Body mass index was also calculated. Result: this study shown that decrease level of Interleukin 20 and chronic kidney disease patient comparing to Healthy controls group , and this also associated with increase in fasting serum sugar , Glycated Hemoglobin , Urea , Creatinine and body mass index in patients group compared to Healthy controls group. Conclusion: serum Interleukin 20 level show significance difference between patients and Healthy controls groups. that’s lower in patients groups.