Relationship Between GERD-Q Score with Esophagitis Findings in Endoscopy

Billy Siahaan,Arles Arles,Wirhan Azhari

doi:10.24871/2132020177-181

Billy Siahaan, Arles Arles + Show 1 more

Open Access

https://doi.org/10.24871/2132020177-181

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Abstract

Background: Gastro-esophageal Reflux Disease (GERD) is a disease that is commonly found in daily practice and affecting the patients’ quality of life negatively. GERD-Q is a tool in the form of validated questionnaire that is quite useful and easy to use in daily practice to diagnose GERD by symptoms and signs especially in primary care that do not have endoscopy facilities. This study was built to assess the correlation between GERD-Q score and esophagitis finding in upper gastrointestinal endoscopy in Pekanbaru. Method: This was a prospective cross-sectional study with sample groups of GERD-Q score ≥8 (high GERD-Q score) and GERD-Q score 8 (low GERD-Q score) which underwent upper gastrointestinal endoscopy to assess reflux esophagitis. GERD-Q score data were obtained by direct interview.Results: This study was participated by 65 subjects with reflux esophagitis and 51 non-esophagitis patients that had undergone upper gastrointestinal endoscopy procedure. The 65 subjects with reflux esophagitis were divided into groups based on severity (LA Classification), Grade A 29 subjects (45%), Grade B 23 subjects (35%), Grade C 11 subjects (16%), and Grade D 2 subjects (3%). The result of this study showed that there was a statistically significant correlation between GERD-Q score category with esophagitis findings from upper gastrointestinal endoscopy (p 0.05, PR = 2.6)Conclusion: There is a statistically significant correlation between GERD-Q score and esophagitis findings from endoscopy but no relevance in esophagitis severity.

Highlights

Gastro-esophageal reflux disease (GERD) is a disease that is commonly found in daily practice and affecting the patients’ quality of life negatively
The result of this study showed that there was a statistically significant association between GERD-Q score ≥ 8 and esophagitis findings from upper gastrointestinal endoscopy (p < 0.05, Prevalence Risk (PR) = 2.6) compare with GERD-Q score < 8
This study showed that patients with obesity (36.9%) and overweight (27.7%) were the largest body mass index (BMI) categories in esophagitis subject group

Summary

Introduction

Gastro-esophageal reflux disease (GERD) is a disease that is commonly found in daily practice and affecting the patients’ quality of life negatively. A report from Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital Jakarta shows that from 127 subjects that taken upper gastrointestinal endoscopy, 22.8% (30 subjects) have esophagitis. There is study from Syam et al that taken from 1718 patients who underwent upper gastrointestinal endoscopy in 5 years (1997-2002), This study told us that there was a serious increase of esophagitis prevalence from 5.7% in year 1997 to 25.18% in year 2002 (average 13.13% per year).[2] This number seems to be going to elevate in the future years ahead, considering the worsened lifestyle and habits change in the last decade. The advances in medical technology, especially on gastrointestinal endoscopy technique imaging like narrow band imaging, i-scan and other diagnostic instruments such as 24-hour pH-metry and manometry may affect this number by increasing diagnostic detection rate for GERD and mucosal break in esophageal gastric junction.[2].

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