Relationship between genetic diversity and fertility status of hydatid cysts of Echinococcus granulosus isolated from human and some intermediate hosts in Thi-Qar province / Iraq

Abstract

The cestod Echinococcus granulosus produces hydatid cysts, which are an endemic zoonotic in Iraq. This study was conducted to assess the common strains and the effect of haplotype diversity on the fertility status isolated of hydatid cysts from livers of humans and other different organs of intermediate hosts (sheep, cattle, buffalo, and camels), by three mitochondrial DNA genes, including cox1, nad1 and atp6 extracted from the fertile cysts protoscolices and sterile cysts germinal layer. The result indicated that the sheep (G1 ,95%) and buffalo (G3, 5%) strains were responsible for the hydatid cyst infection. All isolates were recorded in the Genbank with numbers ranging from (OL655428- OL655447) for cox1, (OM117505-OM 117524) for nad1and (OM117525- OM117544) for atp6. The current study revealed windingly that no correlation between the haplotype of parasite and the sterility of hydatid cysts. Thus, our finding indicated that environmental factors might play a key role in the fertility of hydatid cysts.