Relationship between fatty liver and metabolic syndrome in T2DM patients by ROC curve

Abstract

Objective To study the relationship between non-alcoholic fatty liver disease (NAFLD) and metabolic disease(MS) in type 2 diabetes mellitus (T2DM).Methods Three hundred and twenty cases of T2DM patients were divided into MS group and Non-MS group.Body mass index (BMI),blood pressure,blood lipids,liver function and the morbidity of NAFLD were evaluated.The relation between NAFLD and MS was analyzed by receiver operating characteristic (ROC) curve.Results The detection rate of NAFLD was 44.1％.MS patients had higher BMI,diastolic blood pressure,serum triglycerides(Tg),gamma-glutamyltransferase(GGT) and the morbidity of NAFLD than Non-MS group (P ＜ 0.05).Pearson relative analysis demonstrated that MS was related to NAFLD (r =0.44,P ＜ 0.01) and serum GGT (r =0.19,P ＜ 0.01).The area under the ROC curve of NAFLD was 0.72(P ＜ 0.01),in the middle of BMI,TG and blood pressure,high-density lipoprotein cholesterol.Conclusions Type 2 diabetes patients complicated with NAFLD are phone to have MS. Key words: Type 2 diabetes mellitus; Metabolic syndrome; Fatty liver; Receiver operating characteristic curve