Abstract
The correlation between domains structure of the fibrinogen molecule and the exon/intron composition of the genes encoding the three fibrinogen polypeptide chains has been analysed. A coincidence of the borders between structural domains and corresponding exons in the N-terminal parts of the molecule was revealed, while no such correlation was found in the C-terminal parts. The analysis indicates that the domain structure of the fibrinogen molecule and the exon/intron structure of its genes evolved independently during the later stage of evolution. This analysis also allowed delineation of the exact borders between some domains and prediction of the existence of additional domains in the central part of the fibrinogen molecule.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
