Relationship between Estradiol Level, Transvaginal Ultrasound Endometrial Thickness, Body Mass Index and Endometrial Pathology in Women with Postmenopausal Bleeding

Abstract

Background: menopause is derived from the Greek words; men (month) and pauses (Cessation). A woman is considered menopausal after cessation of menstruation for 1 year after an average age of 46. Postmenopausal bleeding (PMB) is defined as bleeding recurring in a menopausal woman at least 1 year after cessation of cycles. It must always be investigated because many causes are premalignant or malignant. The most common premalignant and malignant causes are complex hyperplasia with atypia and carcinoma of the endometrium. These disorders are present in as many as 1/3 of the patients evaluated for PMB in many series. Objective: this study aimed to explore the relationship between estradiol level, transvaginal ultrasound, endometrial thickness and body mass index and their correlation to endometrial pathology in women with postmenopausal bleeding. Patients and Methods: in the present study, 80 patients with postmenopausal bleeding were examined regarding BMI, ultrasonographic assessment of endometrial thickness and pathological findings of the endometrium. DC this applies equally to affluent countries and third world. Endometrial biopsy is the ‘‘gold standard’’ for diagnosing abnormalities in the endometrial tissue of patients with PMB.