Abstract

Blood lead concentration and erythrocyte protoporphyrin (PROTO) levels were determined in workers with a occupational exposure to lead. The exposure time of the workers was from 3 to 18 years.n the lead workers, the concentration of blood lead was 32±13μg/100ml and the erythrocyte PROTO levels were 147±102μg/100ml RBC. On the other hand, the normal levels obtained from healthy men with no history of lead exposure were 10±3μg/100ml for the blood lead and 43±17μg/100ml RBC for the erythrocyte PROTO.In the lead-exposed workers, there were a significant positive correlation be-tween the logarithm of erythrocyte PROTO and blood lead levels (r=0.6263, P< 0.001). In addition, the equation of the regression line was as follows: Log10 PROTO=0.0127 Blood lead+1.6808From this investigation, it will be demonstrated that the measurement of ery-throcyte PROTO together with the test of δ-aminolevulinate dehydratase which had often been carried out is available for detecting the degree of lead absorption in workers occupationally exposed to lead.

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