Abstract

BackgroundPrevalence of men with cardiometabolic risk factors (CMRF) is increasing in Japan. Few studies have comprehensively examined the relation between lifestyles and CMRF.MethodsWe examined the baseline data from 3,498 male workers ages 19 to 69 years who participated in the high-risk and population strategy for occupational health promotion (HIPOP-OHP) study at 12 large-scale companies throughout Japan. The physical activity of each participant was classified according to the International Physical Activity Questionnaire (IPAQ). Dietary intake was surveyed by a semi-quantitative Food Frequency Questionnaire. We defined four CMRF in this study as follows: 1) high blood pressure (BP): systolic BP ≥ 130 mmHg, or diastolic BP ≥ 85 mmHg, or the use of antihypertensive drugs; 2) dyslipidemia: high-density lipoprotein-cholesterol concentration < 40 mg/dl, or triglycerides concentration ≥ 150 mg/dl, or on medication for dyslipidemia; 3) impaired glucose tolerance: fasting blood sugar concentration ≥110 mg/dl; 4) obese: a body mass index ≥ 25 kg/m2.ResultsThose who had 0 to 4 CMRF accounted for 1,597 (45.7%), 1,032 (29.5%), 587 (16.8%), 236 (6.7%), and 44 (1.3%) participants, respectively, in the Poisson distribution. Poisson regression analysis revealed that independent factors that contributed to the number of CMRF were age (b = 0.020, P < 0.01), IPAQ (b = -0.091, P < 0.01), alcohol intake (ml/day) (b = 0.001, P = 0.03), percentage of protein intake (b = 0.059, P = 0.01), and total energy intake (kcal)(b = 0.0001, P < 0.01). Furthermore, alcohol intake and its frequency had differential effects.ConclusionsAlcohol intake, percent protein and total energy intake were positively associated, whereas drinking frequency and IPAQ were inversely associated, with the number of CMRF.

Highlights

  • Prevalence of men with cardiometabolic risk factors (CMRF) is increasing in Japan

  • The mean SBP, DBP, body mass index (BMI), alcohol intake, percentage of high blood pressure (BP), dyslipidemia, impaired glucose tolerance (IGT), obese status, and of protein intake were higher among the groups with a higher number of CMRF

  • Independent factors that contributed to the number of CMRF were age, IPAQ (b = -0.091, P < 0.01), alcohol intake (b = 0.001, P = 0.03), percentage of protein intake (%kcal)(b = 0.059, P = 0.01), and total energy intake(b = 0.0001, P < 0.01)

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Summary

Introduction

Few studies have comprehensively examined the relation between lifestyles and CMRF. The prevalence of men with cardiometabolic risk factors (CMRF) is increasing in Japan. CMRF such as high blood pressure (BP), dyslipidemia, impaired glucose tolerance (IGT), and obesity tend to cluster together and it is closely related to insulin resistance [1,2,3,4]. The clustering of CMRF is known as metabolic syndrome (MetS), and is thought to be related to daily lifestyle habits, including nutrient intake, physical activity, smoking and alcohol consumption. The objective of the present study was to examine cross-sectionally the relation between lifestyle habits including physical activity, smoking, dietary intake, alcohol intake and its frequency, and the number of CMRF in Japanese workers, and to find ways of preventing development of CMRF

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