Relationship between D-dimer levels and survival in a sample of Iraqi patients with COVID-19

Abstract

Coronavirus disease 2019 was discovered in December 2019, Wuhan, China. It was transmitted globally producing the COVID-19 pandemic. Coagulopathy is one of the most common complications characterized by an increased D-dimer level. Objective: The aim of this study were to assessment the relationship between the levels of D-dimer and other biomarkers with survival in a sample of Iraqi patients with COVID-19. Methods: A cross section study included 103 patients affected by COVID-19, diagnosed by PCR and chest CT scan, (18 to 70 years old), and admitted at the isolation centers of the Khalis General Hospital and the Shifa Center in Baquba Teaching Hospital Diyala\ Iraq between November 2020 to end January 2021. The patients were divided into two groups: Group 1:(63) survivors patients, Group 2: (40) non survivors patients. Results: The patients divided into groups: 61.2% survivors patients ,38.8% non-survivors adult COVID-19 patients. The results include several biomarkers, each biomarker (mean± SE) was calculated in survivors and non-survivors patients. Serum ferritin, plasma D-dimer showed statistical significant increasing in non-survivors group (1777.8 ± 126.02, 3985.42 ± 1224.95) than survivors patients group (1182.7 ± 142.45, 1857.50 ± 291.21) with p-value ≥ 0.05.