Abstract
Abstract Objective: To investigate the relationship between air fine particulate matter (PM2.5) and plasma vWF level in healthy young adults during the 2008 Olympic Games in Beijing. Methods: 114 healthy young adults working and living in Peking University First Hospital were recruited. Six blood samples at pre-Olympics, during-Olympics and post-Olympics were taken from these individuals for plasma vWF measurement. Daily concentrations of PM2·5 were measured. Results: The change tendency of average concentration of PM2.5 were consistent with the change tendency of average plasma vWF level. The influence of PM2.5 on plasma vWF level had a 4 days lag effect (P<0.05). Conclusion: The average plasma vWF level in the 114 normal individuals lowered in association with the decrease of PM2.5 during the 2008 Olympic Games in Beijing. Improvement of air pollution is beneficial to prevent some diseases, especially cardiovascular diseases.
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