RELATIONSHIP BETWEEN COGNITIVE DISORDER AND METABOLIC SYNDROME IN ELDERS IN A BRAZILIAN COMMUNITY

Abstract

A metabolic syndrome (MS) is associated with factors of cardiovascular risk possibly related to increased risks of Cognitive Disorders (CD)1,4,5. Genetic, environmental and lifestyle factors are some of the responsible for the line of predisposition and development of metabolic diseases as well as neurodegenerative disorders 2,7,8. cross-sectional, quantitative and correlational study. Were evaluated 110 participants (>65 years), users of public health system in a country town of the state of São Paulo. The following tests were applied: Addenbrooke's Cognitive Examination - Revised (ACE-R)6, Mini-Mental State Examination (MMSE)6, the MS was defined accordingly to the criteria established by the IDF (International Diabetes Federation)2. The sample is composed by majority of female (71.8%), mean 4.5 (±4.1) years of schooling, mean age of 72.3 (±6.4) years, use of medications (76.1%), 40, 9% with high BMI (overweight3), with MS and CD, 6.9% were found. No associations were found in the Chi-Square test between MS and ACE-R (p=.560) and MS with MMSE (p=.138). There was found important correlations using the Spearman's test between Weight X ACE-R(p=0.025/ρ=.213), Weight X ACE-R Attention-Guidance domain (p=.003/ρ=.283), Weight X ACE-R Language (p=0.028/ρ=.290), Weight X MEEM(ACE-R) (p=.007/ρ=.256), also presents correlations between Abdominal Circumference and ACE-R Attention-Guidance domain (p=.032/ρ=.205). CD did not show difference using the Mann-Whitney test when compared to groups with MS and without MS. There was also no difference in the MS to CD group and no CD and the domains that defined by ACE-R. there is no association between a MS and cognition, however, there was with one of its components and weight. As MS can compromise the quality of life in elderly, including testing that assess it can be of great value for a cognitive diagnosis with greater reliability. The adjustments of the components of MS at their ideal levels may be important for the prevention of CD.