Relationship between Chinese visceral adipose index and obstructive sleep apnea hypopnea syndrome in patients with type 2 diabetes mellitus

Abstract

Sleep apnea hypopnea index(AHI) was evaluated in 304 patients with T2DM using a portable sleep apnea monitor. Patients were divided into 4 groups as T2DM without obstructive sleep apnea hypopnea syndrome(OSAHS) group, T2DM with mild, moderate and severe OSAHS groups according to AHI. Patients were divided into 4 groups according to CVAI. The results suggested that the prevalence of OSAHS was 61.8% among hospitalized T2DM patients. There were significant differences in body mass index, waist circumference, Chinese visceral adipose index(CVAI), high density lipoprotein cholesterol, triglyceride and alanine aminotransferase among groups(all P<0.05). There were significant positive correlations between CVAI and AHI, GGT, ALT, AST, HOMA-IR(all P<0.01). CVAI was a risk factor of AHI according to multivariable regression analysis. CVAI may reflect the severity of OSAHS in patients with T2DM and visceral adipose deposition is a risk factor of AHI. (Chin J Endocrinol Metab, 2018, 34: 141-143) Key words: Diabetes mellitus, type 2; Visceral adipose index; Obstructive sleep apnea hypopnea syndrome