Relationship between blood pressure and renal function in patients with acute cerebral infarction complicated with renal injury

Abstract

Objective To investigate the relationship between blood pressure and renal function in patients with acute cerebral infarction complicated with renal injury. Methods A total of 326 patients with acute cerebral infarction and renal injury in Department of Emergency of Henan Provincial People’s Hospital from May 2016 to September 2018 were selected. According to glomerular filtration rate, renal injury was staged, including 160 cases of CKD stage 3 and 94 cases of CKD stage 4 cases, 72 cases of CKD5 stage. Blood pressure was measured in 326 patients. According to the traditional blood pressure classification method, they were divided into normal blood pressure, systolic hypertension, diastolic hypertension, and double-stage hypertension. Results The overall control rate of blood pressure was 44.9%, and it gradually decreased with the increase in CKD stage. The incidences of CKD3, CKD4, and CKD stage 5 diastolic hypertension were 5.2%, 5.3% and 1.0%, respectively. The two stages of hypertension were CKD3, CKD4, and CKD5, which were 15.1%, 14.5%, and 15.9%, respectively. The incidence of systolic hypertension increcreased with the CKD stage increasing, the incidence in CKD3, CKD4, CKD5 period were 28.2%, 39.6% and 45.9%, respectively. Age and CKD stage were independent risk factors for isolated systolic hypertension. The risk of systolic hypertension in patients with CKD4 and CKD was 2.12 and 3.98 times, of that in patients in CKD3. Conclusions The incidence of systolic hypertension is directly proportional to the degree of renal injury in patients with acute cerebral infarction, which may partially contribute to increased cardiovascular mortality during the progress of conclusion kidney injury. Key words: Hypertension; Isolated systolic hypertension; Isolated diastolic hypertension; Acute cerebral infarction