Abstract

This paper focuses on the relationship between blood pressure (BP) and heart rate (HR) during 24 hours in 423 normotensive (NO) and 205 hypertensive (HE) subjects. Although considerable knowledge has been gained about BP and HR signals, their relationship over 24 hours has never been completely described. By using a Holter Blood Pressure Monitor, it was possible to record BP and HR for 24 hours. Systolic, Diastolic and Mean BP in both NO and HE subjects showed four different time intervals presenting well-defined trends The results demonstrated that changes in HR present closely parallel changes in BP with a marked reduction of both signals during nocturnal rest. On the contrary, in the period between 15:30 and 19:30, HR and BP showed an inverse relationship with decreasing heart rate and increasing blood pressure.

Highlights

  • It is well known that variability signals related to cardiovascular system contain relevant information about the behavior of the autonomic nervous system that acts as a controller of many physiological parameters such as heart rate (HR) and blood pressure (BP) [1,2,3]

  • The analysis achieved on both 4-Chicago epidemiologic surveys [6] and a nationwide Belgian population study [7], carried out on approximately 5000 men and 4000 women, showed that HR progressively increased when systolic blood pressure (SBP) and diastolic blood pressure (DBP) increased, with a stronger direct association for SBP than for DBP values

  • Reed et al [8] found a linear relationship between HR and both SBP and DBP in the range 70–90 beats/min

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Summary

Introduction

It is well known that variability signals related to cardiovascular system contain relevant information about the behavior of the autonomic nervous system that acts as a controller of many physiological parameters such as heart rate (HR) and blood pressure (BP) [1,2,3]. HR measurements provide significant prognostic information about cardiovascular risks [4]. Several studies investigated whether the relationship between heart rate and blood pressure was linear [8,9,10,11,12]. Reed et al [8] found a linear relationship between HR and both SBP and DBP in the range 70–90 beats/min. Erikssen and Rodahl [9] reported a constant increase in SBP from 40 to 100 beats/min in adults and Schieken et al [10] observed a similar increase in children

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