Relationship between Atherogenic Indexes and Fasting Blood Sugar among Diabetic Patients

Abstract

Disorders in lipid profile levels participate in the generation of atherogenic dyslipidaemia, complications in patients with type 2 diabetes (T2DM), one of the strongest markers in predicting cardiovascular disease (CVD). In this study we investigated the fast blood sugar (FBS), lipid profile, and atherogenic indexes [atherogenic index of plasma (AIP); cardiac risk ratio (CRR); cardioprotective index (CPI); atherogenic coefficient (AC)] were calculated in males and females and compared control groups. There was a low positive correlation between FBS with a lipid profile ranging from (r = 0.334, P <0.043), to (r = 0.459, P < 0.027), and a very strong between atherogenic indexes with a lipid profile ranging from (r = 0.804, P < 0.000) to (r = 0.950, P <0.000). Conversely, there was a strong negative correlation between CPI and lipid profile ranging from (r = - 0.663, P < 0.000) & (r = - 0.768, P < 0.000) and a very strong negative correlation with LDL (r = - 0.900, P < 0.000) & (r = - 0.905, P < 0.000) in male. In females, the correlation was positive and recorded at (r = 0.213, 0.361) between FBS and TG &VLDL. Besides, very strong correlation between AIP with TG (r = 0.954, P <0.000), TC (r = 0.572, P <0.000), and VLDL (r = 0.456, P <0.029). While the correlation was strong between AC with LDL (r = 0.829, P <0.000), it was very strongly positive with TC (r = 0.943, P <0.000), finally, the correlation value in CPI was highly negative and ranged from (r = - 0.774, P <0.000), to (r = - 0.909, P <0.000), for TC and LDL respectively. In conclusion, the participants with high levels of FBS possess a highly significant positive correlation with atherogenic indexes (AIP, CRR, and AC) and a negative correlation with CPI values.