Abstract

FiveDrosophila species were tested for larval alcohol preference behavior (LAPB) over a range of ethanol concentrations. Four general conclusions came out of the study. (1) Significant interspecific variation in LAPB exists withinDrosophila. (2) The behavioral response is environmentally dependent. (3) Interspecific differences inDrosophila LAPB result from an interplay between two biological factors: alcohol dehydrogenase (ADH)-mediated alcohol catabolism and aldehyde sensitivity. (4) Larval preference for low concentrations of alcohol is independent of relative ADH activity levels.

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