Relationship between admission random blood glucose, fasting blood glucose, with severity of coronary lesion and hospital outcomes in patients admitted with ST elevation myocardial infarction

Abstract

Background: This research addressed the relationships between admission random blood glucose (RBG), fasting blood glucose (FBG), and severity of coronary artery disease (CAD) “assessed by Gensini score “and in hospital outcomes in patient admitted with ST elevated Myocardial Infarction (STEMI). Methods: The research was conducted on 100 cases who were recruited from Cardiology department in Tanta University presented with STEMI and underwent coronary angiography either primary PCI or Pharmaco-invasive, the cases were categorized firstly, according to RBG into two groups: Group 1: Non hyperglycemia group (200 mg/dl). Then after 8hours from admission FBG was tested "regarding FBG Patient is fasting but to be well hydrated" and accordingly the cases were further sub-divided into two groups: Group I: Non-FBG elevated (126 mg/dl). Results: It was shown that there was a significant difference between the hyperglycemic and FBG elevated groups in terms of severity of CAD and In-hospital mortality where both the hyperglycemic and the FBG elevated cases had more extensive CAD and higher Gensini score. Also, the occurrence of major adverse cardiovascular events was higher in these two groups in comparison to their non-hyperglycemic, non FBG elevated counterparts. There was statistically significant positive correlation between Gensini score and RBS and fasting blood glucose level (p