Relationship between admission blood glucose and in-hospital adverse events of elderly patients with non-ST-segment elevation myocardial infarction combined with multi-organ dysfunction in emergency department

Abstract

Objective To investigate the relationship between admission blood glucose and in-hospital adverse events of elderly patients with non-ST-segment elevation myocardial infarction(NSTEMI) combined with multi-organ dysfunction in emergency department, and to assess the prognostic value. Methods Fifty-one geriatric patients with NSTEMI combined with multi-organ dysfunction were selected and divided into the experimental group (26 cases) and control group (25 cases), depending on whether they had adverse events in hospital.After the propensity score matching was used to reduce confounding effects, the difference in admission blood glucose between the two groups was compared.According to the ROC curve, the predictive value of immediate admission blood glucose to the incidence of adverse events during hospitalization was detected. Results After propensity score matching, admission blood glucose of the experimental group ( (10.35±4.06) mmol/L) was higher than that of the control group ( (7.05±2.45) mmol/L), and this difference was statistically significant (t=2.869, P<0.01). The area under the ROC curve for adverse events during hospitalization was 0.758 (P<0.01), and it may reach the best prognostic value when we choose 8.025mmol/L as the critical value.Under this condition, the sensitivity was 0.765 and specificity was 0.765. Conclusion For geriatric patients with NSTEMI combined with multi-organ dysfunction in emergency department, admission blood glucose is a risk factor for in-hospital adverse event, and the risk is high when admission blood glucose is over 8.025mmol/L. Key words: Admission blood glucose; Non-ST-segment elevation myocardial infarction; Elderly patient; Adverse event; Propensity score matching