Abstract

Many works have shown the relationship between the outcome of surgical critically ill patient and oxygen availability of the body. Many factors cause an insufficient oxygen availability: tissutal traumatism with the consequent beginning of the inflammatory cascade, anemia, hypotension due to the blood losses, anesthesia. Shoemaker has called this alteration as 'oxygen debt' and has demonstrated that patient outcome is directed correlated to it and that this oxygen debt must be extinguished as soon as possible. The higher is the oxygen debt, higher is the risk of multiple organ failure and death. The gut has certainly a prominent role to determine these two last events and previous studies have shown the importance of a low gastric perfusion to cause death, measuring intramucosal pH with a gastric tonometer. A previous study has shown a correlation between IL-6 levels and outcome in major abdominal surgery. Now we have done a work to investigate the correlation between gut hypossia, measured with sigmoid tonometry, during aortic clamping for abdominal aortic aneurysm operation, and patient outcome.

Highlights

  • In our experience, very often, even with a nonrebreathing mask (NRM), high oxygen delivery to patient with the existent materials is insufficient

  • The difference between both attributable mortality rates (22.1%) was statistically significant

  • P109 How we reduce allogenic blood transfusions in the patients undergoing surgery of ascending aorta D Radojevic, Z Jankovic, B Calija, M Jovic, B Djukanovic

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Summary

Introduction

Very often, even with a nonrebreathing mask (NRM), high oxygen delivery to patient with the existent materials is insufficient. There is evidence that increasing the dose of continuous renal replacement therapy (CRRT) is associated with improved survival in critically ill patients with acute renal failure (ARF) [1]. The aim of this study is to investigate if there is any difference in patients’ characteristics in ICU between COPD and nonCOPD diseases caused chronic respiratory failure and require mechanical ventilation during acute exacerbations. Noninvasive positive pressure ventilation (NPPV) has been reported to be beneficial in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD), and to facilitate weaning In this trial we assessed the possible benefit of early NPPV in patients with blunt chest trauma and acute respiratory failure. The aim of this study was to compare the pharmacokinetic and pharmacodynamic parameters and the clinical efficacy of a continuous infusion of cefepime versus an intermittent regimen in critically ill adults patients with gram negative bacilli infection. The purpose of the study is to identify the factors associated with DNR status in our institution

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