Relationship among metastatic ratio of lymph node and pathology or its prognosis in elderly gastric cancer

Abstract

Objective To study the association between metastatic ratio of lymph node and clinical pathological features and its prognosis in elderly patients with gastric cancer. Methods The first postoperative pathological data of 219 patients with gastric cancer aged ≥60 years were retrospectively analyzed. The relationships of metastatic ratio of lymph node with gender, differentiation degree, depth of tumor invasion, vascular invasion, perineural invasion were analyzed. We used Kaplan-Meier survival analysis and Cox regression model to analyze this relationship. Results The metastasis rate of lymph node was higher in gastric cancer patients with higher degree of differentiation, deeper tumor-infiltration, vascular invasion or neural invasion, and the metastasis rate of lymph node was increased in females than in males (all P<0.05). Kaplan-Meier survival analysis and Cox regression model analysis suggested that the metastasis rate of lymph node was an independent factor for postoperative survival rate in the elderly with gastric cancer. Conclusions The metastatic ratio of lymph node could be used to estimate the clinical prognosis of elderly gastric cancer. Key words: Gastric neoplasms; Tumor metastasis; lymph node; Clinical pathology; Prognosis