Abstract
The relationship between serum testosterone level and the degree of hand preference was studied in right-handed young adults. Hand preference was assessed by the Edinburgh Handedness Inventory. Serum testosterone level was determined using tritium-marked-radioimmunoassay. There was no significant correlation between these variables in males without FS. In males with FS and in females with and without FS, the serum testosterone levels were found to be negatively linearly correlated with the degree of the right-hand preference. Similar results were obtained with respect to foot and eye preferences. It was concluded that not only prenatal testosterone but adult testosterone also may exert a life long influence on cerebral lateralization; this effect seems to be much more pronounced in the female than male brain, which may exert a female-like pattern under genetic control.
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