Abstract
Erythrocytes of whole blood incubated at 37°C underwent large increases in average density and cellular hemoglobin (indicative of volume decrease) soon after depletion of ATP. Coincident were rapid exchanges of cell potassium with plasma sodium ions. The incubation time corresponding to loss of 90% or more of ATP correlated with the onset of cell contraction and rapid cation exchange. This time (approximately 45 hr) in whole blood preserved in ACD was diminished in heparinized blood or ACD blood containing fluoride, approximately the same in four units of previously frozen red cells, and extended by 15 or more hr in whole blood containing adenine, adenine + inosine, or adenine + inosine + guanosine.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
