Abstract
Objective: The prevalence of diabetes mellitus continues to increase worldwide, followed by the incidence of complications, which ends up causing morbidity and mortality in patients. There were many factors related to the incidence of complications in diabetes mellitus. Patient’s adherence to their medication is considered to have an impact on the complications in diabetic patients.
 Methods: The study was conducted on 68 patients with a cross-sectional method with consecutive sampling. Statistical analysis was done using the Chi-square and Fisher’s exact test. p<0.05 was considered statistically significant. Patients were interviewed using a demographic data questionnaire and medication adherence rating scale – 5 (MARS-5). Other data and diagnosis of complications were collected through medical records. The epidemiological analysis was carried out using the prevalence ratio.
 Results: There were 47 (69.1%) patients with type 2 diabetes mellitus (T2DM) hospitalized due to complications, and 56 (82.4%) patients have poor adherence to treatment. There was a significant relationship between treatment adherence and the incidence of complications in diabetes mellitus patients with p = 0.001 and it was found that there was a risk of 3.14 times in patients who have poor adherence to be hospitalized due to complications.
 Conclusion: Treatment adherence affects the incidence of complications in patients with T2DM.
Highlights
Diabetes mellitus has become a global epidemic whose prevalence has continued to increase in recent years
This study aims to determine the association between treatment adherences to the incidence of complications in patients with type 2 diabetes mellitus (T2DM) at Wangaya Hospital
In patients with a history of diabetes mellitus and at least 6 months on medication of oral anti-diabetic regimens and insulin were interviewed and asked to fill the medication adherence rating scale – 5 (MARS-5) questionnaire. This MARS-5 was translated to Bahasa Indonesia and already granted permission to use by the originator of the questionnaire, Professor Robert Horne
Summary
Diabetes mellitus has become a global epidemic whose prevalence has continued to increase in recent years. According to the World Health Organization, there was an increase in the prevalence of diabetes mellitus from 4.7% or 108 million people in 1980 to 8.5% or 422 million people in 2014. There were 1.6 million deaths worldwide due to diabetes mellitus in 2016. As many as 87% of these deaths occurred in low- and middle-income countries. This causes diabetes mellitus to be in the seventh position in the world as the leading cause of death [1,2,3,4,5,6]
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